Search results for "Normal volunteers"
showing 3 items of 3 documents
Performing allocentric visuospatial judgments with induced distortion of the egocentric reference frame: an fMRI study with clinical implications
2003
The temporary improvement of visuospatial neglect during galvanic vestibular stimulation (Scand. J. Rehabil. Med. 31 (1999)117) may result from correction of the spatial reference frame distorted by the responsible lesion. Prior to an investigation of the neural basis of this effect in neurological patients, exploration of the neural mechanisms underlying such procedures in normals is required to provide insight into the physiological basis thereof. Despite their clinical impact, the neural mechanisms underlying the interaction of galvanic (and other) vestibular manipulations with visuospatial processing (and indeed the neural bases of how spatial reference frames are computed in man) remai…
Dependence of motion sickness in automobiles on the direction of linear acceleration.
1982
Thirty-eight normal volunteers were tested in an ambulance car while being accelerated in one of the following positions: (1) sitting upright facing forward in the car, (2) lying supine on a stretcher head forward, (3) supine position head backward. Consecutive short periods of negative horizontal acceleration (0.7–0.95 g) were achieved by brisk braking manoeuvres of the car, followed by weak reacceleration (0.15 g). Motion sickness symptoms were observed and recorded after each experiment using a special motion sickness scaling index which was weighted according to the strength of any particular symptom. The results indicate that horizontal linear acceleration in a car, such as experienced…
Systematic analysis of esophageal pressure topography in high-resolution manometry of 68 normal volunteers
2013
Summary The introduction of high-resolution manometry (HRM) has been a significant advance in esophageal diagnostics. Normative values however are currently based upon a single set of published reference values, and multiple new metrics have been added over the past several years. Our goal was to provide a second set of ‘normal-values’ and to include all current metrics suggested by the 2012 Chicago classification. Sixty-eight subjects without foregut symptoms or previous surgery (median age 25.5 years, ranging from 20–58 years, 53% female) underwent esophageal motility assessment via an established standardized protocol. Normative thresholds were calculated for esophago-gastric junction (E…